These PDE5 inhibitors may cause headache, flushing, drop in blood pressure, or other adverse effects. Rarely reported side effects include: an erection that will not go away priapism. You can take sildenafil with or without food. Take sildenafil at around the same times every day. Your doctor will discuss the best treatment plan for you. People taking nitrates like nitroglycerin Nitrostat or isosorbide mononitrate Imdur should not take PDE5 inhibitors, as doing so could result in a dangerous drop in blood pressure. A phone or video consultation is sometimes required for legal purposes.Sildenafil (Viagra) is used to treat erectile dysfunction (impotence; inability to get or keep an erection) in men. Sildenafil (Liqrev, Revatio) is used to improve the ability to exercise in adults (Liqrev, Revatio) and children 1 year of age and older (Revatio) with pulmonary arterial hypertension (PAH; high blood pressure in the vessels carrying blood to the . About sildenafil (Viagra) Sildenafil is a medicine used to treat erection problems (erectile dysfunction). Sildenafil is also sometimes used to treat pulmonary hypertension (high blood pressure in the blood vessels that supply the lungs). If you have erection problems sildenafil works by temporarily increasing blood flow to your penis when. Erectile dysfunction is when a man has difficulty getting an erection or keeping it long enough for sex. It’s also known as ED or impotence. It happens when not enough blood flows to the penis, preventing an erection. The frequency increases with age, affecting about 50% of men over age 40*; however younger men may also experience ED.