Concomitant use of potent CYP3A4 inhibitors is contraindicated. If you have any problems with the way your liver works, or if you have any problems with the way your kidneys work. Although Priligy 60 mg is not approved, this dose was used to test the withdrawal effects of chronic daily and as needed dosing of Priligy in the treatment of premature ejaculation in a placebo controlled, double blind, parallel group study in which subjects were randomized. The major human metabolite, dapoxetine N-oxide, was negative in tests for bacterial mutagenicity and in vitro clastogenicity. You have to take it hours before you have sex.Priligy contains the active ingredient dapoxetine, which is a selective serotonin reuptake inhibitor (SSRI). It works by boosting the levels of serotonin in the body, causing a delayed reaction in the areas of the brain that cause ejaculation. This means it .  · Priligy (dapoxetine) is used for the treatment of premature ejaculation. Priligy information at test1.ru includes side effects, interactions and indications. Dapoxetine, marketed as Priligy, among others, is a medication used for the treatment of premature ejaculation (PE) in men 18–64 years old. Dapoxetine works by inhibiting the serotonin transporter, increasing serotonin’s action at the postsynaptic cleft, and as a consequence promoting ejaculatory delay.