People with heart conditions should never take ED medications without consulting a doctor. If approved, the provider will issue a prescription. Recent heart or blood vessel problems. Popular ED medications found online include: Viagra sildenafil : As the first FDA-approved PDE5 inhibitor for ED, sildenafil is taken 30 minutes to four hours before sexual intercourse to help achieve and maintain an erection. The mechanism of action for ED pills is simple: They inhibit the PDE5 enzyme which regulates the signals responsible for the smooth muscle tissue. However, others work on a cash-pay basis and don’t partner with insurance companies.The four main medicines taken by mouth for erectile dysfunction are: Avanafil (Stendra). Sildenafil (Viagra). Tadalafil (Cialis). Vardenafil. These medicines are called . How to Get Generic Viagra An inexpensive blood pressure medication might be an option for some men who suffer from erectile dysfunction By Ginger Skinner Last . Taking sildenafil (Viagra) with medications, like oral azole antifungals and ritonavir (Norvir), can put you at higher risk for side effects, such as headaches, flushing, .

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