Tadalafil Adcirca is used to improve the ability to exercise in people with pulmonary arterial hypertension PAH; high blood pressure in the vessels carrying blood to the lungs, causing shortness of breath, dizziness, and tiredness. If you have an erection that lasts for more than 4 hours, you should go to the nearest hospital emergency department. Take all of the tablets for your daily dose at one time each day; do not divide the tablets to take as separate doses. However, because sexual stimulation is required to initiate the local penile release of nitric oxide, tadalafil’s inhibition of PDE5 will have no effect without sexual stimulation. In trials investigating Cialis, the majority of participants receiving the drug experienced a significant improvement in ED and maintained an erection. The results showed the combination to be even more effective than either medication alone.Tadalafil – STADA T20 – 20 Milligramm. Tadalafil, sold under the brand name Cialis among others, is a medication used to treat erectile dysfunction, benign prostatic hyperplasia, and pulmonary arterial hypertension. [4] [5] [7] It is taken by mouth. [7] Onset is typically within half an hour and the duration is up to 36 hours. Tadalafil (Cialis) is taken by mouth either as needed before sexual activity or once daily for erectile dysfunction (ED).It’s also taken once daily to treat symptoms from an enlarged prostate (benign prostatic hyperplasia, or BPH).Tadalafil (Cialis) is available both as brand-name and generic tablets. Common side effects of this medication include . For the as-needed dose, plan to take Cialis at least 30 minutes before sexual activity, but bear in mind it may take as long as 2 hours to take effect. Also, Cialis requires sexual stimulation to.