Stop using vardenafil and call your doctor at once if you have: ringing in your ears, or sudden hearing loss; irregular heartbeat; swelling in your hands, ankles, or feet; shortness of breath; a light-headed feeling, like you might pass out; or seizure convulsions. Levitra Drug Interactions Levitra is a widely-used medication that can be taken by most men without issues. Inform your healthcare provider about other conditions. Grapefruit and Seville oranges may interact with vardenafil and cause side effects. Popular searches. This is a very uncommon side effect of PDE5 inhibitors.Generic: $ to $ for ten 10 mg tablets But your out-of-pocket cost for Levitra may depend on a few different factors that can drop these costs significantly, . Levitra is not a cure for ED and you still need to be aroused for the medication to work. Levitra and its generic version (vardenafil) are available in doses of: milligrams. 5 milligrams.  · Levitra should be taken approximately 60 minutes before sex, either with or without food. Make sure that you’re familiar with how to use Levitra before taking it prior to sex. Look into other ED medications. Other medications for ED, such as sildenafil, tadalafil and Stendra, offer similar effects to Levitra. Depending on your personal needs.